My dear Unstoppable friends,

It’s hard not to feel a little sentimental at this time of year. A moment for a deep exhale as we reflect on the year that was — the joy, the triumphs, the losses and goodbyes, the new births and welcomes. Life really is a rollercoaster, isn’t it.

And yet, with all of that, my heart is full of gratitude that you and I are right here, right now. Many have not been so fortunate, so let’s not take a single moment for granted.

I’ve learnt so much this year, and I hope you feel that you’ve grown too. It’s been an extraordinary year, and we are all richer for having shared it together.

So this Christmas, as the world feels heavy in places and uncertain in others, I’m choosing to hold onto a simple truth that has carried humanity through every season:

Where there is darkness, there is light.
Where there is hatred, there is love.
Where there is doubt, there is hope.

May your days be filled with light, love, and hope — because I truly believe that when those live in your heart, nothing is impossible.

And with that spirit of light and hope, let’s turn our attention to the small, powerful choices that shape our health, our minds, and the lives we’re building — one day at a time.

My beautiful ones, I wish you the most wonderful Christmas. Wherever you are, may your day be filled with family, friends, laughter, and warmth.

Much love and sunshine, ☀️
Sandy xx

 


Issue #99 • 21 December, 2025

🌅 Rise Report

Protect Your Brain Health Naturally.

Is your sleep position helping or hurting you?

Think your sleep position doesn’t matter? Harvard and Johns Hopkins sleep experts have news for you. Where you position your body for 8 hours every night can significantly impact your heart health, brain function, and how well your body clears toxins.

Over 60% of adults naturally sleep on their side, making it the most common position—and emerging research suggests this instinct might be protecting our brains. Studies show side sleeping, particularly on your left side, optimises your glymphatic system—your brain’s waste clearance system that removes beta-amyloid proteins associated with Alzheimer’s disease.

Dr. Rachel Salas, a Johns Hopkins sleep neurologist, explains that whilst sleep position matters less when you’re young and healthy, it becomes crucial as you age.

Side sleeping keeps airways open (essential for preventing sleep apnoea), takes pressure off your lower back, and in pregnant women, improves blood flow to the uterus and baby.

Back sleeping? It’s the worst position for sleep apnoea—gravity pulls your tongue and soft tissues into positions that block breathing. Some people only have symptoms when they sleep on their backs. Stomach sleeping strains your neck and isn’t recommended for most people.

A 2023 study also found a “relatively strong association” between back sleeping and the neurodegeneration found in Alzheimer’s and Parkinson’s disease.

The takeaway? Your body cycles through positions naturally during the night—nobody stays in one spot—but favouring side sleeping, especially your left side, might be one way to protect your brain and heart.

 

Pass the Brie: It Might Protect Your Brain

25-Year Swedish Study Links High-Fat Cheese to 29% Lower Dementia Risk

Grab the cheese board my friend. A massive 25-year Swedish study tracking 27,670 adults just flipped conventional dietary wisdom on its head – and in a direction I must say I love!

People who ate 50 grams or more of high-fat cheese daily—about two slices of cheddar—had a 13% lower overall dementia risk. For vascular dementia specifically? A stunning 29% lower risk.

High-fat cheeses include cheddar, Brie, Gouda, parmesan—anything over 20% fat content.

And it’s not just cheese. High-fat cream showed similar benefits with people consuming at least 20 grams daily (about 1.4 tablespoons) had a 16% lower dementia risk.

Here’s the twist: no such association appeared for low-fat cheese, low-fat cream, milk, butter, yogurt, or kefir. Only full-fat cheese and cream showed protective effects.

It appears that cheese is fermented, producing bioactive compounds that may influence inflammation and blood vessels. Quality matters too—grass-fed dairy contains higher omega-3 fatty acids, which are preferentially protective for the brain.

The takeaway? You know all those warnings to avoid full-fat dairy? You can forget them. Natural, full-fat, fermented dairy could be protecting our brains in ways low-fat alternatives simply can’t match.

 

Your Brain’s Five Acts: The 5 Ages Your Brain Actually Goes Through

Your brain doesn’t age on a steady slope—it rewires itself in distinct phases separated by four major turning points.

Cambridge researchers analysed MRI scans from nearly 4,000 people aged from newborns to 90-year-olds and discovered something fascinating: the human brain reorganises itself at ages 9, 32, 66, and 83, creating five distinct phases of neural wiring and re-wiring.

Childhood (birth to 9 years): The brain grows at lightning speed, building and pruning connections as it lays down its core wiring.

Adolescence (9 to 32 years): Networks become more efficient and refined — and yes, adolescence really does stretch into your early 30s.

Adulthood (32 to 66 years): Brain structure stabilises. Personality traits settles, intelligence largely plateaus, and the brain becomes more specialised rather than endlessly flexible.

Early ageing (66 to 83 years): Communication shifts. The brain relies less on whole-brain coordination and more on well-established pathways, favouring experience over speed.

Late ageing (83+ years): Connectivity narrows further. The brain leans heavily on familiar circuits and routines, processing information more locally — not because it’s failing, but because it’s conserving energy and relying on what it knows best.

The take-away? Your brain isn’t passively declining with age — it’s actively reorganising itself, on a schedule. Those turning points (9, 32, 66, 83) align with shifts in identity, sleep, stress tolerance, learning, and mental health, which is why many people feel “not quite themselves” at certain ages — and it’s not weakness.

Brain health isn’t about stopping change; it’s about supporting the phase you’re in, because what helped your brain thrive at 25 isn’t what protects it at 55. And by the way, it’s not until you reach 66, that you can officially say you’re getting older. Or at least, as far as your brain goes.

 


❤️ What’s Hot: 

New! The Rise Circle

After two years, 99 newsletters, and more than 200,000 words, it’s time — actually, it’s well overdue — time, to go deeper.

The Rise has always been about helping you become your own health boss. My wish and hope has always been this: that you think differently about health, you question narratives, avoid the chronic diseases and illnesses that plague modern life — and, most of all, that you enjoy the fullest, happiest, healthiest life you can imagine.

But there’s a lot I haven’t shared yet. Not because it wasn’t important — but because some conversations need more context, more continuity, and more care than a weekly newsletter allows. And some are better had away from public forums.

So this week, I’m opening The Rise Circle.

It’s a safe space for those who want to think more deeply, see more clearly, ask better questions, and connect the dots over time.

This isn’t for everyone. And it’s not meant to be.

But if you’ve felt that pull to go deeper — and you’re ready for a more uncensored Sandy as we take 2026 to the next level — I’d love you to join me. This is your moment.

You can step inside right now.

 


🤓 Smarty Pants

Understanding Dementia (and What You Can Do About It)

There aren’t many people who haven’t been touched by dementia — a parent, a grandparent, a friend, or someone close whose personality slowly faded long before their body did. It’s a devastating diagnosis, and for a long time we’ve been led to believe it’s largely inevitable.

The truth is more nuanced.

Dementia isn’t one disease. It’s an umbrella term for several conditions with different biological drivers — which means there are different levers we can pull to reduce risk and support brain health across life.

Here are the main types, in plain English:

Alzheimer’s disease

The most common form.
Characterised by amyloid plaques and tau tangles that disrupt communication between brain cells. Memory loss is often the first sign.

👉 This is where good-quality, regular sleep = a healthy glymphatic system quietly clearing debris from the brain each night.

During deep sleep, the brain’s clean-up system becomes highly active, flushing out waste — including amyloid — that builds up during the day.

Vascular dementia

The second most common — and often the most preventable. Caused by reduced blood flow to the brain from strokes, mini-strokes, or chronically damaged blood vessels.

👉 This is where heart health = brain health becomes very real.
Blood pressure, insulin resistance, inflammation, and circulation all directly shape brain function.

Lewy body dementia

Caused by abnormal protein deposits in the brain. It often involves visual hallucinations, fluctuating attention, sleep disturbances, and Parkinson’s-like movement symptoms.

👉 This is where sleep, nervous system balance, and dopamine health intersect.

Frontotemporal dementia (FTD)

Often appears earlier in life and affects behaviour, personality, or language before memory.

👉 This is where brain resilience, inflammation control, and early pattern recognition matter.

Mixed dementia

A combination of the above — commonly Alzheimer’s plus vascular damage. This is where multiple lifestyle factors compound over time, not one single cause.

Dementia isn’t always random, and it’s not always inevitable. While we can’t control everything, we can support the systems that keep our brain healthy: blood flow, sleep, metabolic health, inflammation, movement, and light. The earlier we protect them, the more brain resilience we build for later life.


🔥 Deep Dive: TL;DL

Dr Thomas Seyfried: The Metabolic Approach to Cancer

Today’s TL;DL dives into a conversation that could change everything you thought you knew about cancer. Dr Thomas Seyfried is a professor at Boston College with over 200 peer-reviewed publications, building on the work of Otto Warburg, the famous German scientist who discovered that cancer cells ferment glucose into lactic acid.

Dr. Seyfried’s central message? Cancer isn’t a genetic disease—it’s a metabolic one. And in a world where we need to question everything, questioning our understanding of cancer and cancer treatment should be high on our list.

 EP #23: The Metabolic Approach to Cancer & Cancer Treatment With Dr. Thomas Seyfried

Cancer: A Mitochondrial Problem

Here’s the first game-changer: Dr Seyfried argues that it is very difficult to get cancer when your mitochondria are healthy. Why? Because cancer is fundamentally disregulated cell growth, and your mitochondria are the master regulators telling cells when to grow, how fast to grow, and when to stop growing.

When mitochondria become damaged or deficient, cells lose this regulation and start growing out of control. The origin of cancer, according to Dr. Seyfried, is a disruption of normal energy metabolism—a replacement of healthy mitochondrial energy with ancient fermentation pathways that existed hundreds of millions of years ago, before oxygen entered the atmosphere. In Dr. Seyfried’s model, if you keep your mitochondria healthy, you don’t get cancer or chronic diseases for that matter.

 

The Two Fuels Driving Cancer

Cancer cells run on just two fuels: glucose and glutamine. Dr. Seyfried’s research showed a direct relationship in brain cancer—the higher the blood sugar, the faster the tumour grew. When they used a keto-genic diet and fasting to lower blood glucose, tumours grew much slower.

Dr. Seyfried shows this pattern was repeated across all cancer types. Higher blood glucose means faster tumour growth and poorer survival in breast cancer, colon cancer, lung cancer, pancreatic cancer. The tumour is literally sucking down glucose and glutamine, and those two fuels drive disregulated growth.

 

The Metabolic Solution

When you lower blood sugar through dietary intervention, your body starts mobilising fat. Your liver converts fatty acids into ketone bodies, which your brain and heart can use for energy. Dr. Seyfried explains that cancer cells cannot effectively use ketones because they lack fully functional mitochondria.

So lowering blood glucose and elevating ketones creates a situation where normal cells get healthier and tumour cells get weaker. Then, with strategic targeting of glutamine, you can manage the disease whilst actually improving overall health—reducing diabetes, high blood pressure, and other metabolic conditions at the same time.

 

Why Isn’t This Standard Treatment?

Dr. Seyfried doesn’t hold back: “Most oncologists have no clue that glucose drives tumour growth. The very people supposed to help you don’t know the biology or biochemistry of the disease they’re managing.” Despite cancer remaining one of the leading causes of death worldwide, the medical establishment continues pushing expensive drugs that can kill as easily as they help, whilst metabolic therapy—backed by solid science—remains virtually unknown in cancer clinics and excluded from medical training and curriculum.

 

The Bottom Line

Cancer is a disease of energy metabolism that can be managed by targeting the two fuels driving it. The science is solid, yet nowhere on the planet is there a clinical trial simultaneously targeting glucose and glutamine whilst transitioning the body to nutritional ketosis.

Dr. Seyfried’s message is clear: you actually get better and healthier when you do metabolic therapy—not worse. The tools exist. The biology is well understood. What’s missing is implementation.


☀️ Sandy’s Sunshine

When Conventional Treatment Feels Like the Only Choice

This year, my brother-in-law Chris passed away just days after his 60th birthday. A few months earlier, he’d been diagnosed with two brain tumours. By the time he died, there were nine.

Chris followed the conventional treatment plan—not because he wanted to, but because he felt he had no other choice. The doctors were clear: this is what you do. This is the standard of care. This is your only hope.

For Chris, he felt overwhelmed. Any prospect of a different path was beyond him. The information was too unfamiliar, too much, and when you’re facing this type of diagnosis, this is completely understandable.

Presenting new information when someone is going through a life threatening situation isn’t the best time. Nervous systems are already maxed out. The standard treatment timeline doesn’t give you space to breathe, let alone research. Surgery is scheduled. Radiation starts. Chemo protocols begin. The machine moves fast, and you’re just trying to survive each day.

Alternative approaches require research, planning, medical team buy-in, family support. They require bandwidth. You need to know what you’d do, before anything happens.

I share this with deep respect for anyone walking this path — and with the quiet hope that one day, people are given more time, more understanding, and more real choice.

Inside The Rise Circle, I go deeper into Dr Seyfried’s work — the metabolic framework he lays out, why he urges caution before disturbing tumours and doing biopsies, and the questions he believes families deserve the space to ask.

 


🔢 Number Crunch

20–30%: the reduction in dementia risk associated with regular physical activity. Movement feeds the brain. See you outside!

 

“What is coming into the world will change the world.”
— Thomas Merton

The information in this newsletter is for educational purposes only and not intended as medical advice. Always consult with a healthcare professional for personal health decisions. This post may contain affiliate links for Daylight computer, and I may earn a small commission if you make a purchase, at no extra cost to you.